Premarin Vaginal Cream is a female sex hormone (estrogen). It is a part of female hormone replacement therapy which helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness.

Premarin Vaginal Cream should be applied all over the vagina as per the provided instructions by the doctor. Even if your symptoms improve, you should continue the treatment as it has been prescribed.

When you start using this medicine you may experience irritation or itching. This usually goes away if you continue using it. You may also get pain in your abdomen, a genital rash, headache and vaginal thrush (candidiasis). Tell your doctor if you have bleeding in your vagina. Your doctor may give you an alternative medicine.